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Who we are

Halozyme Therapeutics

Halozyme Therapeutics is a biopharmaceutical company developing and commercializing products targeting the extracellular matrix for the diabetes, oncology, dermatology, and drug delivery markets. The company's product portfolio is primarily based on intellectual property covering the family of human enzymes known as hyaluronidases and additional enzymes that affect the extracellular matrix.

Halozyme's EnhanzeTM technology is a novel drug delivery platform designed to increase the absorption and dispersion of biologics. The company has key partnerships with Baxter, Roche, ViroPharma and Intrexon to apply Enhanze technology to biological therapeutics, including immunoglobulin, Herceptin®, MabThera®, Cinryze® and alpha 1-antitrypsin. Halozyme’s Ultrafast Insulin program combines its rHuPH20 enzyme with mealtime insulins, which may produce more rapid absorption, faster action, and improved glycemic control. The product candidates in Halozyme's pipeline target significant areas of unmet medical need.

What's new

Halozyme Begins Phase 2 Trial with PEGPH20

Halozyme initiated a Phase 2 clinical trial investigating its proprietary recombinant enzyme, PEGPH20, plus gemcitabine in the treatment of patients with previously untreated Stage IV pancreatic cancer. PEGPH20 is believed to increase a chemotherapeutic agent’s ability to penetrate into a tumor and increase the treatment’s effectiveness by degrading the protective extra cellular matrix surrounding the tumor cells. The trial will study the safety, tolerability and efficacy of gemcitabine plus PEGPH20 with a primary endpoint of overall survival.