Broad Range of Partnered and Proprietary Products



PRODUCT, COLLABORATION PRODUCTS
AND PRODUCT CANDIDATES
THERAPEUTIC
AREA
RESEARCH FOCUS
(PARTNER)
  • Preclinical
  • Phase 1
  • Phase 2
  • Phase 3
  • Filed
  • Approved

ONCOLOGY PIPELINE & PRODUCT CANDIDATES

 
 
 
 
 
 
PEGPH20 with ABRAXANE® (nab-paclitaxel)
and gemcitabine
Oncology
Pancreas Cancer
 
 
 
 
 
 
PEGPH20 with KEYTRUDA® (pembrolizumab)
Oncology
Gastric Cancer/Non-Small Cell Lung Cancer
 
 
 
 
 
 
PEGPH20 with HALAVEN® (eribulin)*
Oncology
Breast Cancer (Eisai)
 
 
 
 
 
 
PEGPH20 with TECENTRIQ® (atezolizumab)
Oncology
Pancreas Cancer (Genentech)
 
 
 
 
 
 
PEGPH20 with TECENTRIQ® (atezolizumab)
Oncology
Gastric Cancer (Genentech)
 
 
 
 
 
 
PEGPH20 with TECENTRIQ® (atezolizumab)
Oncology
Gall Bladder Cancer & Cholangiocarcinoma
 
 
 
 
 
 
PEG-ADA2: PEGylated-Human Adenosine
Deaminase 2
Oncology
Various
 
 
 
 
 
 

*No further clinical development planned on the Phase 2 portion of this study.

PRODUCT, COLLABORATION PRODUCTS
AND PRODUCT CANDIDATES
THERAPEUTIC
AREA
APPROVED
INDICATION
  • Preclinical
  • Phase 1
  • Phase 2
  • Phase 3
  • Filed
  • Approved

PROPRIETARY APPROVED PRODUCT

 
 
 
 
 
 
HYLENEX® recombinant
(hyaluronidase human injection)
Various
Adjuvant for subcutaneous fluid delivery for dispersion & absorption of other injected drugs
Approved in the U.S.
 
 
 
 
 
 

ENHANZE® COLLABORATION APPROVED PRODUCTS

Roche

 
 
 
 
 
 
Herceptin® SC (trastuzumab)
Oncology
Breast Cancer
Approved in EU and other countries outside the U.S.
 
 
 
 
 
 
MabThera® SC (rituximab)
(Outside of U.S.)
RITUXAN HYCELA(rituximab)
(rituximab/hyaluronidase human)
(U.S.)
Oncology
Multiple blood cancers
Approved for NHL in the EU and OUS;
Approved for CLL in the EU;
Approved for DLBCL, CLL and FL in the U.S.
 
 
 
 
 
 

Baxalta

 
 
 
 
 
 
HYQVIA® [Immune Globulin Infusion 10% (Human) with Recombinant Human Hyaluronidase]
Immunology
Primary Immunodeficiency
Approved for adults in the EU, U.S., Puerto Rico and Australia; Pediatric indication approved in EU
 
 
 
 
 
 
PRODUCT, COLLABORATION PRODUCTS
AND PRODUCT CANDIDATES
THERAPEUTIC
AREA
RESEARCH
FOCUS
  • Preclinical
  • Phase 1
  • Phase 2
  • Phase 3
  • Filed
  • Approved

ENHANZE® COLLABORATION PRODUCT CANDIDATES

Roche (Total of 9 potential targets)

 
 
 
 
 
 
PERJETA® (pertuzumab)*
Oncology
Breast Cancer
 
 
 
 
 
 
Undisclosed
Undisclosed
Undisclosed
 
 
 
 
 
 
Pfizer (Total of 6 potential targets)
Undisclosed
 
 
 
 
 
 

Janssen (Total of 5 potential targets)

 
 
 
 
 
 
DARZALEX® (daratumumab)
Oncology
Amyloidosis
Smoldering Myeloma
Multiple Myeloma
Multiple Myeloma
Multiple Myeloma
Multiple Myeloma
 
 
 
 
 
 
AbbVie (Total of 9 potential targets)
Undisclosed
 
 
 
 
 
 
Lilly (Total of 5 potential targets)
Undisclosed
 
 
 
 
 
 
Bristol-Myers Squibb (Total of 11 potential targets)
PD-1 target
Oncology
 
 
 
 
 
 
Alexion (Total of 4 potential targets)
ALXN1210 SC
Various
 
 
 
 
 
 

All trademarks belong to their respective owners.

*Plans for Phase 3 fixed-dose combination with Herceptin in 2018.

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